Solvent/non‐solvent sintering: A novel route to create porous microsphere scaffolds for tissue regeneration
نویسندگان
چکیده
منابع مشابه
Microsphere-based scaffolds for cartilage tissue engineering: using subcritical CO(2) as a sintering agent.
Shape-specific, macroporous tissue engineering scaffolds were fabricated and homogeneously seeded with cells in a single step. This method brings together CO(2) polymer processing and microparticle-based scaffolds in a manner that allows each to solve the key limitation of the other. Specifically, microparticle-based scaffolds have suffered from the limitation that conventional microsphere sint...
متن کاملPorous ceramic bone scaffolds for vascularized bone tissue regeneration.
Hydroxyapatite scaffolds with a multi modal porosity designed for use in tissue engineering of vascularized bone graft substitutes were prepared by three dimensional printing. Depending on the ratio of coarse (mean particle size 50 microm) to fine powder (mean particle size 4 microm) in the powder granulate and the sintering temperature total porosity was varied from 30% to 64%. While macroscop...
متن کاملOvalbumin-Based Porous Scaffolds for Bone Tissue Regeneration
Cell differentiation on glutaraldehyde cross-linked ovalbumin scaffolds was the main focus of this research. Salt leaching and freeze drying were used to create a three-dimensional porous structure. Average pore size was 147.84 ± 40.36 μm and 111.79 ± 30.71 μm for surface and cross sectional area, respectively. Wet compressive strength and elastic modulus were 6.8 ± 3.6 kPa. Average glass trans...
متن کاملA Review on Commonly Used Scaffolds in Tissue Engineering for Bone Tissue Regeneration
Introduction: Bone is one of the tissues that have a true potential for regeneration. However, sometimes the bone defects are so outsized that there is no chance of bone self-repair and restoration or the damage is such that it is not possible to repair with medical or surgical interventions. In these situations, bone grafts are the treatment of choice, but due to several obstacles, including l...
متن کاملIncreased Osteogenic Potential of Pre-Osteoblasts on Three-Dimensional Printed Scaffolds Compared to Porous Scaffolds for Bone Regeneration
Background: One of the main challenges with conventional scaffold fabrication methods is the inability to control scaffold architecture. Recently, scaffolds with controlled shape and architecture have been fabricated using 3D-printing. Herein, we aimed to determine whether the much tighter control of microstructure of 3DP PLGA/β-TCP scaffolds is more effective in promoting osteogenesis than por...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biomedical Materials Research Part B: Applied Biomaterials
سال: 2008
ISSN: 1552-4973,1552-4981
DOI: 10.1002/jbm.b.31033